AICDA gene related symptoms and diseases
All the information presented here about the AICDA gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,ORPHANET,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to AICDA gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Immunodeficiency | Uncommon - Between 30% and 50% cases |
| Lymphadenopathy | Uncommon - Between 30% and 50% cases |
| Recurrent bacterial infections | Uncommon - Between 30% and 50% cases |
| IgA deficiency | Uncommon - Between 30% and 50% cases |
| IgG deficiency | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with AICDA gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Recurrent infection of the gastrointestinal tract
- Impaired Ig class switch recombination
- Recurrent upper and lower respiratory tract infections
- Opportunistic infection
Rare diseases associated to AICDA gene
Here you will find a list of rare diseases related to the AICDA. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
HYPER-IGM SYNDROME TYPE 2
Alternate names
HYPER-IGM SYNDROME TYPE 2 Is also known as activation-induced cytidine deaminase deficiency, aid deficiency, higm2
More info about HYPER-IGM SYNDROME TYPE 2
SOURCES: ORPHANET
IMMUNODEFICIENCY WITH HYPER-IGM, TYPE 2; HIGM2
Alternate names
IMMUNODEFICIENCY WITH HYPER-IGM, TYPE 2; HIGM2 Is also known as hyper-igm syndrome 2
Description
Hyper-IgM syndrome type 2 (HIGM2) is a rare immunodeficiency characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE, resulting in a profound susceptibility to bacterial infections.For a discussion of genetic heterogeneity of immunodeficiency with hyper-IgM, see HIGM1 (OMIM ).
Most common symptoms of IMMUNODEFICIENCY WITH HYPER-IGM, TYPE 2; HIGM2
- Immunodeficiency
- Lymphadenopathy
- Recurrent bacterial infections
- IgA deficiency
- IgG deficiency
More info about IMMUNODEFICIENCY WITH HYPER-IGM, TYPE 2; HIGM2
SOURCES: OMIM
Search interest in AICDA
Potential gene panels for AICDA gene
Hyper IgM Syndrome (HIGM): (AICDA for HIGM2) (Full Gene Sequencing) Panel
Canada.
By Molecular Diagnostic Laboratory University of Alberta
This panel specifically test the AICDA gene.
More info about this panel Canada.
Hyper IgM Syndrome (HIGM): (AICDA for HIGM2) (Known Mutation) Panel
Canada.
By Molecular Diagnostic Laboratory University of Alberta
This panel specifically test the AICDA gene.
More info about this panel Canada.
Hyper IgM Syndrome (HIGM): Four-gene Profile (AICDA, UNG, CD40, CD40LG) (Full Gene Sequencing) Panel
Canada.
By Molecular Diagnostic Laboratory University of Alberta Hyper IgM Syndrome (HIGM): Four-gene Profile (AICDA, UNG, CD40, CD40LG) (Full Gene Sequencing) that also includes the following genes: CD40 CD40LG UNG AICDA
More info about this panel Canada.
Hyper IgM Syndrome (HIGM): Two-gene Profile (AICDA, UNG) (Full Gene Sequencing) Panel
Canada.
By Molecular Diagnostic Laboratory University of Alberta Hyper IgM Syndrome (HIGM): Two-gene Profile (AICDA, UNG) (Full Gene Sequencing) that also includes the following genes: UNG AICDA
More info about this panel Canada.
Hyper IgM Syndrome (HIGM): Three-gene Profile (AICDA, UNG, CD40) (Full Gene Sequencing) Panel
Canada.
By Molecular Diagnostic Laboratory University of Alberta Hyper IgM Syndrome (HIGM): Three-gene Profile (AICDA, UNG, CD40) (Full Gene Sequencing) that also includes the following genes: CD40 UNG AICDA
More info about this panel Canada.
Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication Panel
United States.
By ARUP Laboratories, Molecular Genetics and Genomics Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication that also includes the following genes: SH2D1A BTK CD40 CD40LG UNG VAV1 AICDA BLNK CD19 CD79A
More info about this panel United States.
AICDA Gene Sequencing Panel
United States.
By GeneDx
This panel specifically test the AICDA gene.
More info about this panel United States.
AICDA. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the AICDA gene.
More info about this panel Spain.
Humoral dysfunction Del/Dup Panel Panel
United States.
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Humoral dysfunction Del/Dup Panel that also includes the following genes: SH2D1A BTK STAT1 STAT3 CD27 CD40LG UNG IKZF1 AICDA LRBA
More info about this panel United States.
Humoral dysfunction Seq Analysis Panel
United States.
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Humoral dysfunction Seq Analysis that also includes the following genes: SH2D1A BTK STAT1 STAT3 CD27 CD40LG UNG IKZF1 AICDA LRBA
More info about this panel United States.
Humoral dysfunction Seq + Del/Dup Panel Panel
United States.
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Humoral dysfunction Seq + Del/Dup Panel that also includes the following genes: SH2D1A BTK STAT1 STAT3 CD27 CD40LG UNG IKZF1 AICDA LRBA
More info about this panel United States.
Immunodeficiency with hyper-IgM type 2 (sequence analysis of AICDA gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the AICDA gene.
More info about this panel Portugal.
Immunodeficiency with hyper IgM type 2 Panel
Germany.
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders
This panel specifically test the AICDA gene.
More info about this panel Germany.
Hyper IgM Syndrome Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Hyper IgM Syndrome Sequencing Panel with CNV Detection that also includes the following genes: SH2D1A BTK CD40 CD40LG UNG AICDA MRE11 NBN NFKBIA ATM
More info about this panel United States.
Hyper IgM Syndrome via AICDA Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the AICDA gene.
More info about this panel United States.
AID gene Panel
United States.
By Immunology Diagnostics Laboratory Seattle Children's Research Institute
This panel specifically test the AICDA gene.
More info about this panel United States.
AICDA Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht
This panel specifically test the AICDA gene.
More info about this panel Netherlands.
B cell pathology panel Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht B cell pathology panel that also includes the following genes: BTK CD40 CD40LG UNG AICDA BLNK CD19 CD79A CD79B CD81
More info about this panel Netherlands.
Immunodeficiency type 2, with hyper-IgM Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the AICDA gene.
More info about this panel Germany.
CentoICU platinum plus Panel
Germany.
By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panel Germany.
New Born testing (CentoICU) Panel
Germany.
By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panel Germany.
Antibody deficiencies Panel Panel
Germany.
By CeGaT GmbH Antibody deficiencies Panel that also includes the following genes: BTK TCF3 TCF4 CD40 TNFSF12 CD40LG UNG AICDA BLNK RTEL1
More info about this panel Germany.
Single gene testing AICDA Panel
Germany.
By CeGaT GmbH
This panel specifically test the AICDA gene.
More info about this panel Germany.
Invitae Monogenic Autoimmunity Panel Panel
United States.
By Invitae Invitae Monogenic Autoimmunity Panel that also includes the following genes: RMRP SH2D1A SLC7A7 BTK STAT1 STAT3 STAT5B STIM1 STX11 STXBP2
More info about this panel United States.
Invitae Monogenic Inflammatory Bowel Disease Panel Panel
United States.
By Invitae Invitae Monogenic Inflammatory Bowel Disease Panel that also includes the following genes: SH2D1A BTK STAT1 STAT3 STIM1 STXBP2 CD40LG WAS ZAP70 AICDA
More info about this panel United States.
Invitae Primary Immunodeficiency Panel Panel
United States.
By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2
More info about this panel United States.
Invitae Hyper IgM Syndrome Panel Panel
United States.
By Invitae Invitae Hyper IgM Syndrome Panel that also includes the following genes: CD40LG UNG AICDA
More info about this panel United States.
Early Onset Inflammatory Bowel Disease: Sequencing Panel Panel
United States.
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Early Onset Inflammatory Bowel Disease: Sequencing Panel that also includes the following genes: SH2D1A BTK STXBP2 CD40LG WAS AICDA HPS4 LRBA DCLRE1C HPS6
More info about this panel United States.
Early Onset Inflammatory Bowel Disease: Deletion/Duplication Panel Panel
United States.
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Early Onset Inflammatory Bowel Disease: Deletion/Duplication Panel that also includes the following genes: SH2D1A BTK STXBP2 CD40LG WAS AICDA HPS4 LRBA DCLRE1C HPS6
More info about this panel United States.
AICDA Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the AICDA gene.
More info about this panel United States.
Primary Immunodeficiency Panel Panel
Finland.
By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK
More info about this panel Finland.
Immunodeficiency with hyper-IgM, type 2 Panel
Spain.
By Bioarray
This panel specifically test the AICDA gene.
More info about this panel Spain.
HYPER-IgM SYNDROME TYPE 2 (AUTOSOMAL RECESSIVE) Panel
Spain.
By Laboratorio de Genetica Clinica SL
This panel specifically test the AICDA gene.
More info about this panel Spain.
Hyper IgM Syndrome Type 2 , Sequencing AICDA Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the AICDA gene.
More info about this panel Spain.
Common Variable Immune Deficiency and Related Disorders, Panel Massive Sequencing (NGS) 41 Genes Panel
Spain.
By Reference Laboratory Genetics Common Variable Immune Deficiency and Related Disorders, Panel Massive Sequencing (NGS) 41 Genes that also includes the following genes: CXCL12 SH2D1A BTK STAT1 STAT3 TGFB1 TNFRSF4 CD40 CD40LG AICDA
More info about this panel Spain.
Hyper IgM Syndrome ,Panel Massive Sequencing (NGS) 4 Genes Panel
Spain.
By Reference Laboratory Genetics Hyper IgM Syndrome ,Panel Massive Sequencing (NGS) 4 Genes that also includes the following genes: CD40 CD40LG UNG AICDA
More info about this panel Spain.
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