Ovarian Hyperstimulation Syndrome

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.

Genes related to Ovarian Hyperstimulation Syndrome

FSHR

View recommended genes panels

Clinical Features

Top most frequent phenotypes and symptoms related to Ovarian Hyperstimulation Syndrome

Abdominal pain
Nausea and vomiting
Infertility
Nausea
Hirsutism
Ascites
Abdominal distention
Aspiration
Abnormality of the genitourinary system
Pleural effusion

And another 10 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Alternative names

Ovarian Hyperstimulation Syndrome Is also known as ovarian hyperstimulation syndrome, familial gestational spontaneous, ohss.

Researches and researchers

Doctors, researchs, and experts related to Ovarian Hyperstimulation Syndrome extracted from public data.

Ovarian Hyperstimulation Syndrome Experts map

Current Researchs and researchers

ILLKIRCH-GRAFFENSTADEN — Pr Stéphane VIVILLE
Investigator of research project
- Institution/s:
  — IGBMC - CNRS UMR 7104 - Inserm U 1258, Institut de génétique et de biologie moléculaire et cellulaire - IGBMC
- Research area/topic::
  Exome sequencing in a consanguineous family with spontaneous ovarian hyperstimulation cases with unknown triggers

Ovarian Hyperstimulation Syndrome Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Premature Ovarian Failure Sequencing Panel. By Genetic Services Laboratory University of Chicago (United States). BMP15, FOXL2, MCM8, PSMC3IP, HFM1, NOBOX, FIGLA, FSHR, LMNA, NR5A1 Specificity 10 % Genes 100 %
Premature Ovarian Failure Deletion/Duplication Panel. By Genetic Services Laboratory University of Chicago (United States). BMP15, FOXL2, MCM8, PSMC3IP, HFM1, NOBOX, FIGLA, FSHR, LMNA, NR5A1 Specificity 10 % Genes 100 %
FSHR. Complete sequencing. By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain). FSHR Specificity 100 % Genes 100 %
46,XX gonadal dysgenesis (sequence analysis of FSHR gene). By CGC Genetics (Portugal). FSHR Specificity 100 % Genes 100 %
46,XX gonadal dysgenesis (FSH receptor polymorphisms). By CGC Genetics (Portugal). FSHR Specificity 100 % Genes 100 %
Ovarian Dysgenesis 1. By Laboratory of Genetics BioTe21 Adam Master (Poland). FSHR Specificity 100 % Genes 100 %
Ovarian Dysgenesis and Ovarian Hyperstimulation Syndrome via FSHR Gene Sequencing with CNV Detection. By PreventionGenetics PreventionGenetics (United States). FSHR Specificity 100 % Genes 100 %
Female Infertility Sequencing Panel with CNV Detection. By PreventionGenetics PreventionGenetics (United States). BMP15, SEMA3A, SEMA3E, FOXL2, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, TAC3, TACR3, WNT4, WT1, WWOX, ZP1, ARL6 , (...) View the complete list with 84 more genes Panel complete gene list BMP15, SEMA3A, SEMA3E, FOXL2, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, TAC3, TACR3, WNT4, WT1, WWOX, ZP1, ARL6, WDR11, CBX2, SPRY4, PROKR2, MCM8, TRIM32, IL17RD, PSMC3IP, ARX, PROK2, BBS7, TTC8, HFM1, PADI6, CHD7, CLPP, MCM9, RSPO1, LHX4, NOBOX, FEZF1, FIGLA, MAMLD1, CYP11A1, CYP17A1, CYP19A1, BBS10, BBS12, CCDC141, SOHLH1, DHH, SYCE1, DMRT1, DMRT2, NSMF, NUP107, BBS9, DUSP6, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, AIRE, FGF17, FGF8, FGFR1, FGFR2, FLRT3, AKR1C4, FSHB, FSHR, GALT, GNRH1, GNRHR, KISS1R, HESX1, HFE, HS6ST1, HSD17B3, ANOS1, KISS1, AR, LEP, LEPR, LHB, LHCGR, LHX3, LMNA, MAP3K1, MKKS, NR0B1, NR3C1, NR5A1, PCSK1, ATRX, AXL, POR, PRLR, PROP1, BBS1, BBS2, BBS4, BBS5 Specificity 1 % Genes 100 %

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Sources and references

You can check the following sources for additional information.

ORPHANET MESH OMIM Rare Disease Search Engine

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