Esophagitis, Eosinophilic, 1; Eoe1

Description

Eosinophilic esophagitis (EOE) has an incidence of approximately 1 per 10,000 people. Symptoms include difficulty feeding, failure to thrive, vomiting, epigastric or chest pain, dysphagia, and food impaction. Individuals with EOE are predominantly young males with a high rate of atopic disease, and the diagnosis is made by endoscopy and biopsy findings of isolated eosinophils in the esophagus (summary by Rothenberg et al., 2010). Genetic Heterogeneity of Eosinophilic EsophagitisEosinophilic esophagitis-1 (EOE1) is associated with variation at chromosome 7q11.2. Another locus (EOE2 ) has been been associated with variation in the TSLP gene (OMIM ) on chromosome 5q22.

Clinical Features

Top most frequent phenotypes and symptoms related to Esophagitis, Eosinophilic, 1; Eoe1

Failure to thrive
Edema
Dysphagia
Vomiting
Gastroesophageal reflux
Chest pain
Esophagitis
Esophageal stricture
Esophageal stenosis
Epigastric pain

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Incidence and onset information

— Based on the latest data available Esophagitis, Eosinophilic, 1; Eoe1 have a estimated prevalence of 40.08 per 100k in Europe.

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Alternate names

Esophagitis, Eosinophilic, 1; Eoe1 Is also known as esophagitis, eosinophilic;ee;eoe.

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