Cowden Syndrome 4; Cws4

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Genes related to Cowden Syndrome 4; Cws4

KLLN

View recommended genes panels

Clinical Features

Phenotypes and symptoms related to Cowden Syndrome 4; Cws4

Hamartoma
Renal neoplasm
Abnormality of the gingiva
Trichilemmoma
Abnormality of buccal mucosa

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Cowden Syndrome 4; Cws4 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
KLLN. By Fulgent Genetics Fulgent Genetics (United States). KLLN Specificity 100 % Genes 100 %
Hereditary Cancer Comprehensive Panel. By NeoGenomics Laboratories NeoGenomics Laboratories, Inc. (United States). RUNX1, SDHB, SDHC, SDHD, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TERC, TERT, TP53, TP53BP1, VHL, WT1, XRCC2, CDH1, CDK4, CDKN2A, CEBPA , (...) View the complete list with 52 more genes Panel complete gene list RUNX1, SDHB, SDHC, SDHD, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TERC, TERT, TP53, TP53BP1, VHL, WT1, XRCC2, CDH1, CDK4, CDKN2A, CEBPA, CHEK1, GALNT12, GREM1, BRIP1, MYH14, CTNNA1, ABRAXAS1, PALB2, GEN1, MYH15, ETV6, KLLN, AKT1, GATA2, HOXB13, APC, SMAD4, MEN1, MLH1, MRE11, MSH2, MSH6, MUTYH, MYH1, MYH10, MYH11, MYH13, MYH2, MYH3, MYH4, MYH6, MYH7, MYH8, MYH9, NBN, ATM, NTRK1, ATR, PIK3CA, PMS2, POLD1, POLE, PPM1D, PRSS1, BAP1, BARD1, PTEN, RAD50, RAD51, RAD51C, RAD51D, RET Specificity 2 % Genes 100 %
Tempus xT assay. By Tempus Labs, Inc. (United States). BCL6, RIT1, BCL7A, BCR, ROS1, RPL5, RPS15, RPS6KB1, RUNX1, RXRA, BLM, SDHA, SDHB, SDHC, SDHD, SEC23B, SEMA3C, BMPR1A, SF3B1, SRSF2 , (...) View the complete list with 555 more genes Panel complete gene list BCL6, RIT1, BCL7A, BCR, ROS1, RPL5, RPS15, RPS6KB1, RUNX1, RXRA, BLM, SDHA, SDHB, SDHC, SDHD, SEC23B, SEMA3C, BMPR1A, SF3B1, SRSF2, SGK1, SCG5, FOXL2, BRAF, BRCA1, BRCA2, SLIT2, SMARCA1, SMARCA4, SMARCB1, SMARCE1, ARID1A, SMC1A, KDM5C, SMO, SOD2, SOX10, SOX2, SOX9, SPINK1, SPOP, SRC, BTG1, BTK, STAG2, STAT3, STAT4, STAT5A, STAT5B, STAT6, STK11, AURKB, AURKA, BUB1B, SYK, EPCAM, TAF1, TBX3, HNF1A, HNF1B, TCF3, TCF7L2, TCL1A, TERT, TGFBR2, NKX2-1, TMPRSS2, TNF, TNFAIP3, TNFRSF14, TNFRSF17, CD40, FAS, TNFRSF9, CD70, MED12, TOP1, TOP2A, TP53, TPM1, TPMT, TRAF3, EGLN1, TSC1, TSC2, TYMS, U2AF1, UGT1A1, UGT1A9, UMPS, KDM6A, VEGFA, VHL, WEE1, NSD2, WRN, WT1, XPA, XPC, XPO1, XRCC1, XRCC2, XRCC3, ACTA2, ZNF217, KAT6A, IKZF1, BCL11B, BRD4, FBXO11, CTCF, KMT2C, HDAC4, CIC, NSD1, CRLF2, PPP1R15A, NHP2, NOP10, CALR, IKBKE, CASP8, CASR, RUNX1T1, CBFB, CBL, CBLB, CBR3, P2RY8, SETBP1, CCND1, CCND2, KMT2B, CCND3, CCNE1, CBLC, TP63, CD19, CARD11, CD22, SUFU, SLC49A4, KIF1B, FBXW7, CDC73, BCLAF1, HSPH1, FRS2, CD79A, CD79B, PIAS4, RNF139, PALLD, ARHGAP26, DICER1, SUZ12, ACVR1B, POT1, ARID5B, CDH1, SPEN, CD274, CDK4, CDK6, CDK8, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C, ARID2, ARID1B, EMSY, RSF1, ZNRF3, PHF6, ERRFI1, ASXL1, CEBPA, IFNL3, SETD2, HAVCR2, RNF43, KLHL6, PDCD1LG2, CCDC6, CFTR, CKS1B, CHD2, CHD4, CHEK1, SOCS1, GALNT12, GREM1, SPRED1, AJUBA, BRIP1, DIS3, FANCL, BCOR, FOXQ1, MIB1, QKI, RINT1, PREX2, ZRSR2, NUDT15, FANCM, KEAP1, CREBBP, CRKL, SLX4, CDK12, CSF1R, CSF3R, SMC3, TENT5C, YEATS4, DOT1L, UBE2T, CTLA4, CTNNA1, CTNNB1, CTRC, FANCI, CUX1, CXCR4, BCORL1, ABRAXAS1, CYLD, ZNF750, TET2, CYP1B1, SDHAF2, TMEM127, PALB2, CTC1, CYP2D6, CYP3A5, SLC47A2, DAXX, AMER1, TIGIT, GEN1, DDB2, DDR2, FLCN, DDX3X, TMEM173, RICTOR, DIS3L2, DKC1, TANC1, TBL1XR1, SH2B3, DYNC2H1, DNM2, DNMT3A, PBRM1, VSIR, DPYD, SLC26A3, TUSC3, RPTOR, CEP57, EBF1, EGF, EGFR, ELF3, ENG, EP300, EPHA2, EPHA7, EPHB1, EPHB2, EPOR, ERBB2, ERBB3, ERBB4, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, ERG, ETS1, ETS2, ETV1, ETV4, ETV5, ETV6, EWSR1, EZH2, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FAT1, FCGR2A, FCGR3A, FDPS, FGF1, FGF10, FGF14, FGF2, FGF23, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, FGFR1, FGFR2, FGFR3, FGFR4, FH, FHIT, KLLN, FLG, FLT1, FLT3, FLT4, FNTB, FOXO1, FOXO3, FOXP1, AKT1, AKT2, AKT3, MTOR, ABCB1, FUBP1, G6PD, GATA1, GATA2, GATA3, GATA4, GATA6, ALK, TAP1, GLI1, GNA11, GNA13, GNAQ, GNAS, TAP2, GPC3, GPS2, GRIN2A, ARHGAP35, GRM3, GSTP1, H19, HIST1H1E, H3F3A, HIST1H4E, HAS3, HDAC1, HDAC2, HGF, HIF1A, HLA-A, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DQB2, HLA-DRA, HLA-DRB1, HLA-DRB5, HLA-E, HLA-F, HLA-G, FOXA1, HOXB13, HRAS, HSP90AA1, IDH1, IDH2, ABCC3, IFIT1, IFIT2, IFIT3, IFNAR1, IFNAR2, IFNGR1, IFNGR2, APC, BIRC3, IL10RA, IL15, IL2RA, IL6R, IL7R, IDO1, ING1, INPP4B, IRF1, IRF2, IRF4, IRS2, ITPKB, JAK1, JAK2, JAK3, JUN, KDR, KEL, KIT, KRAS, MAFB, AR, ARAF, LAG3, LDLR, LMNA, LMO1, RHOA, LRP1B, LYN, LZTR1, MAD2L2, SMAD2, SMAD3, SMAD4, MAF, MALT1, MAP2K1, MAP2K2, MAP2K4, MAP3K1, MAP3K7, MAPK1, MAX, MC1R, MCL1, MDM2, MDM4, MEF2B, MEN1, MET, MGMT, CIITA, MITF, MKI67, MLH1, MLH3, KMT2D, MLLT3, MPL, MRE11, MS4A1, MSH2, MSH3, MSH6, MTAP, MTHFR, MTRR, MUTYH, ASNS, MYB, MYC, MYCL, MYCN, MYD88, MYH11, ABL1, NBN, NCOR1, NCOR2, ABL2, NF1, ZFHX3, NF2, NFE2L2, NFKBIA, NOTCH1, NOTCH2, NOTCH3, NPM1, ATIC, ATM, NRAS, NRG1, NT5C2, NTHL1, NTRK1, NTRK2, NTRK3, NUP98, PAK1, PRKN, PAX5, PAX7, PAX8, PCBP1, ATP7B, PDCD1, PDGFRA, PDGFRB, PDK1, PDPK1, ATR, ATRX, PIK3C2B, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIM1, AXIN1, AXIN2, AXL, PLCG2, PML, PMS1, PMS2, B2M, PHOX2B, POLD1, POLE, POLH, POU2F2, PPP2R1A, PPP2R2A, PPP6C, PRCC, PRDM1, PRKAR1A, PRSS1, PRSS2, BAP1, BARD1, PTCH1, PTCH2, PTEN, PTPN11, PTPN13, PTPN22, PTPRD, RAC1, RAD21, RAD50, RAD51, RAD51C, RAD51B, RAD51D, RAD54L, RAF1, RANBP2, RARA, RASA1, RB1, KDM5A, BCL10, RBM10, BCL2L1, BCL2L11, RECQL4, RET Specificity 1 % Genes 100 %

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Search Engine

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